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TACE/ADAM-17 phosphorylation by PKC-epsilon mediates premalignant changes in tobacco smoke-exposed lung cells.
PloS one, 2011;[epublish]6(3):e17489.
Sulf-2: an extracellular modulator of cell signaling and a cancer target candidate.
Expert opinion on therapeutic targets, Sep-2010;14(9):935-49.
EMMPRIN regulates the canonical Wnt/beta-catenin signaling pathway, a potential role in accelerating lung tumorigenesis.
Oncogene, Jul-22-2010;29(29):4145-56. Epub 2010 May 31.
Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis.
Oncogene, Feb-4-2010;29(5):635-46. Epub 2009 Oct 26.
Use of a phage display antibody to measure the enzymatic activity of the Sulfs.
Methods in enzymology, 2010;480:51-64.
Epithelial-mesenchymal transition in lung cancer: is tobacco the "smoking gun"?
American journal of respiratory cell and molecular biology, Jul-2006;35(1):3-9. Epub 2006 Feb 16.
Wnt and Hedgehog are critical mediators of cigarette smoke-induced lung cancer.
PloS one, 2006;[epublish]1:e93.
Tobacco smoke control of mucin production in lung cells requires oxygen radicals AP-1 and JNK.
The Journal of biological chemistry, Sep-10-2004;279(37):39085-93.
Viral dsRNA activates mucin transcription in airway epithelial cells.
FEBS letters, Oct-9-2003;553(1-2):33-8.
Tobacco smoke-induced lung cell proliferation mediated by tumor necrosis factor alpha-converting enzyme and amphiregulin.
The Journal of biological chemistry, Jul-11-2003;278(28):26202-7.
Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells.
Nature medicine, Jan-2002;8(1):41-6.
Mechanisms by which gram-positive bacteria and tobacco smoke stimulate mucin induction through the epidermal growth factor receptor (EGFR).
Novartis Foundation symposium, 2002;248:171-6; discussion 176-80, 277-82.
The transcriptional responses of respiratory epithelial cells to Bordetella pertussis reveal host defensive and pathogen counter-defensive strategies.
Proceedings of the National Academy of Sciences of the United States of America, Dec-5-2000;97(25):13847-52.
Control of mucin transcription by diverse injury-induced signaling pathways.
American journal of respiratory and critical care medicine, Nov-1999;160(5 Pt 2):S44-8.
Balance between MMP-9 and TIMP-1 expressed by human bronchial epithelial cells: relevance to asthma.
Annals of the New York Academy of Sciences, Jun-30-1999;878:512-4.